Hair loss affects millions of people, and finding an effective solution can be challenging. Advances in regenerative medicine have introduced innovative, non-surgical treatments to stimulate hair growth and restore hair health. Two of the most promising options are PRF (Platelet-Rich Fibrin) injections and PRP (Platelet-Rich Plasma) therapy. PRF vs. PRP for Hair Loss: Both treatments harness the body’s natural healing properties to rejuvenate hair follicles and promote thicker, fuller hair. But what are the differences, and which one is right for you? Let’s explore these cutting-edge therapies in detail.
What Does PRF Mean?
PRF stands for Platelet-Rich Fibrin, a revolutionary hair restoration treatment derived from your own blood. This procedure involves drawing a small sample of blood, which is then spun in a centrifuge at a lower speed compared to PRP. This gentle spinning process allows for the preservation of valuable growth factors, cytokines, and stem cells, which are essential for stimulating hair follicles and promoting natural hair growth.
Unlike PRP, PRF does not contain anticoagulants or other additives. This results in a fibrin matrix that holds the growth factors in place, releasing them gradually to prolong the regenerative effects. This slower release makes PRF injections a powerful and sustained treatment for individuals experiencing hair thinning or hair loss.
How PRF Works for Hair Loss
The PRF hair restoration process is simple and minimally invasive:
- Blood Collection: A small sample of your blood is drawn, similar to a routine blood test.
- Centrifugation: The blood is spun at a lower speed to separate and preserve platelets, growth factors, and stem cells.
- Injection: The PRF solution is carefully injected into areas of the scalp where hair thinning or loss is occurring.
These growth factors and stem cells stimulate inactive hair follicles, encouraging new hair growth and improving the thickness and quality of existing hair. Patients typically begin to see noticeable improvements within two to three months following treatment.
What Is PRP Therapy for Hair?
PRP (Platelet-Rich Plasma) therapy is another advanced treatment for hair loss. Similar to PRF, PRP involves drawing blood and using a centrifuge to separate the platelets. However, PRP is spun at a higher speed and typically includes anticoagulants to prevent clotting. While PRP contains powerful growth factors, it does not have the additional stem cells or fibrin matrix found in PRF.
How Does PRP Therapy Work?
- Blood Draw: A small amount of blood is collected from the patient.
- Centrifuge Process: The blood is processed to isolate the platelet-rich plasma.
- Injection: The PRP is injected directly into the scalp to stimulate hair follicles.
PRP accelerates tissue regeneration and increases blood flow to the hair follicles, encouraging hair growth. Patients usually see improvements after three to four treatments, spaced a few weeks apart.

PRF vs. PRP: Key Differences
While both PRF and PRP are effective for promoting hair growth, there are key differences that may influence which treatment is best for you:
Feature | PRF (Platelet-Rich Fibrin) | PRP (Platelet-Rich Plasma) |
Centrifuge Speed | Lower speed (preserves more growth factors) | Higher speed (fewer growth factors) |
Additives | No anticoagulants or chemicals | Contains anticoagulants |
Growth Factors | Higher concentration with stem cells | High concentration, no stem cells |
Release of Growth Factors | Gradual, sustained release | Immediate release |
Results Timeline | Visible in 2-3 months | Visible in 3-4 treatments |
Treatment Frequency | Fewer sessions needed | Requires multiple sessions |
Are PRF Injections Safe?
Yes, PRF injections are safe because they utilize your body’s natural substances without synthetic additives. This minimizes the risk of allergic reactions or adverse side effects. Both PRF and PRP treatments are minimally invasive, require little to no downtime, and have been shown to be effective in clinical studies. Mild swelling or redness at the injection site is normal and typically subsides within a day or two.
Which Treatment Is Right for You?
Deciding between PRF and PRP depends on several factors, including your age, overall health, and the extent of your hair loss. PRF may be the better option if you seek a more potent and longer-lasting treatment with stem cell activation, while PRP remains a reliable choice for boosting hair growth and improving scalp health.
At Jolie Med Spa, our expert team will assess your unique needs and recommend the most effective treatment plan. We use state-of-the-art technology and personalized techniques to deliver exceptional results tailored to your goals.
Experience the Future of Hair Restoration
Don’t let hair loss hold you back. With PRF and PRP therapy, you can achieve thicker, fuller hair without surgery or extended downtime. Our team at Jolie Med Spa is here to guide you through every step of your hair restoration journey.
Contact us today to schedule your consultation and discover the best solution for your hair loss concerns!